In the nematode C.elegans, insulin signaling regulates development and aging in response to the secretion of numerous insulin peptides.Here, we describe a novel, non-signaling isoform of the nematode insulin receptor (IR), DAF-2B, NUTRI SEA OMEGA 3 that modulates insulin signaling by sequestration of insulin peptides.DAF-2B arises via alternative s
Why Do People Living with HIV Adhere to Antiretroviral Therapy and Not Comorbid Cardiovascular Disease Medications? A Qualitative Inquiry
Charles Muiruri,1,2 Isabelle P Sico,1 Julie Schexnayder,3 Allison R Webel,3 Nwora Lance Okeke,4 Christopher T Longenecker,5 Juan Marcos Gonzalez,1 Kelley A Jones,1 Sarah E Gonzales,1 Hayden B Bosworth1 1Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA; 2Duke Global Health Institute, Duke University, Durh
Hydrodynamic Performance of a Hybrid System Combining a Fixed Breakwater and a Wave Energy Converter: An Experimental Study
In this paper, a hybrid system integrating a fixed breakwater and an oscillating buoy type wave energy converter (WEC) is introduced.The energy converter is designed to CLA 1000MG extract the wave power by making use of the wave-induced heave motions of the three floating pontoons in front of the fixed breakwater.A preliminary experimental study is
The Impact of Chlorhexidine as an Endodontic Irrigant/Medicament on Post-Obturation Pain in Patients Following Endodontic Therapy: A Preliminary Bayesian Meta-Analysis
To CINNAMON QUILLS assess the overall impact of chlorhexidine, when used as an endodontic irrigant/medicament, on post-obturation pain following endodontic treatment by the application of Bayes methods of meta-analysis.This study aimed to combine recently documented evidence using rigorous and specific search criteria.The available data were analyz
Assessment of common housekeeping genes as reference for gene expression studies using RT-qPCR in mouse choroid plexus
Abstract Choroid plexus (ChP), a vascularized secretory epithelium located in all brain ventricles, plays critical roles in development, homeostasis and brain repair.Reverse transcription quantitative real-time PCR (RT-qPCR) is a popular and useful technique for measuring gene expression changes and also widely used in ChP studies.However, the reli